Diagnosing and Treating Lupus (2024)

Talk to your doctor if you have lupus symptoms.Lupus is a chronic disease with no cure.This means that you can manage it with treatment, but it will not go away. Treatment can help improve your symptoms, prevent flares, and prevent other health problems often caused by lupus. Your treatment will depend on your symptoms and needs.

How is lupus diagnosed?

Lupus can be hard to diagnose because it has many symptoms that are often mistaken for symptoms of other diseases. Many people have lupus for a while before they find out they have it. If you have symptoms of lupus, tell your doctor right away.

Diagnosing and Treating Lupus (1)

No single test can tell if a person has lupus. But your doctor can find out if you have lupus in other ways, including:

  • Medical history. Tell your doctor about your symptoms and other problems. Keep track of your symptoms by writing them down when they happen. Also, track how long they last.
  • Family history of lupus or other autoimmune diseases. Tell your doctor if lupus or other autoimmune diseasesrun in your family.
  • Complete physical exam. Your doctor will look for rashes and other signs that something is wrong.
  • Blood and urine tests. The antinuclear antibody (ANA) test can show if your immune system is more likely to make the autoantibodies of lupus. Most people with lupus test positive for ANA. But, a positive ANA does not always mean you have lupus. If you test positive for ANA, your doctor will likely order more tests for antibodies that are specific to systemic lupus erythematosus (SLE).
  • Skin or kidney biopsy. A biopsy is a minor surgery to remove a sample of tissue. The tissue is then viewed under a microscope. Skin and kidney tissue looked at in this way can show signs of an autoimmune disease.

Your doctor may use any or all of these tests to make your diagnosis. They also can help your doctor rule out other diseases that can be confused with lupus.

How is lupus treated?

There is no cure for lupus but treatments can help you feel better and improve your symptoms. Your treatment will depend on your symptoms and needs. The goals of treatment are to:

  • Prevent flares
  • Treat symptoms when they happen
  • Reduce organ damage and other problems

Your treatment might include medicines to:

  • Reduce swelling and pain
  • Calm your immune system to prevent it from attacking the organs and tissues in your body
  • Reduce or prevent damage to the joints
  • Reduce or prevent organ damage

What types of medicines treat lupus?

Several different types of medicines treat lupus. Your doctors and nurses may change the medicine they prescribe for your lupus as your symptoms and needs change.

Types of medicines commonly used to treat lupus include:

  • Nonsteroidal anti-inflammatory drugs (NSAIDs). Over-the-counter NSAIDs, such as ibuprofen and naproxen, help reduce mild pain and swelling in joints and muscles.
  • Corticosteroids. Corticosteroids (prednisone) may help reduce swelling, tenderness, and pain. In high doses, they can calm the immune system. Corticosteroids, sometimes just called “steroids,” come in different forms: pills, a shot, or a cream to apply to the skin. Lupus symptoms usually respond very quickly to these powerful drugs. Once this has happened, your doctor will lower your dose slowly until you no longer need it. The longer a person uses these drugs, the harder it becomes to lower the dose. Stopping this medicine suddenly can harm your body.

Talk to your doctor:

  • About any side effects you may have
  • If your medicines no longer help your symptoms
  • If you have new symptoms
  • If you want to become pregnant
  • About any vitamins or herbal supplements you take — they might not mix well with medicines you use to treat lupus

Can I treat my lupus with alternative medicine?

Some people with lupus try creams, ointments, fish oil, or supplements they can buy without a prescription. Some people try homeopathy or see a chiropractor to care for their lupus. Some people with lupus who try these types of treatments say that they help.

Research studies have not shown any benefits to these types of treatments. And research studies have not been done to see if these treatments hurt people with lupus.

Talk to your doctor or nurse before trying any alternative medicine. Also, don’t stop or change your prescribed treatment without first talking to your doctor or nurse.

Will I need to see a special doctor for my lupus?

Maybe. Start by seeing your family doctor and a rheumatologist, a doctor who specializes in the diseases of joints and muscles such as lupus. Depending on your symptoms or whether your organs have been hurt by your lupus, you may need to see other types of doctors. These may include nephrologists, who treat kidney problems, and clinical immunologists, who treat immune system disorders.

Can I die from lupus?

Yes, lupus can cause death. But, thanks to new and better treatments, most people with lupus can expect to live long, healthy lives. The leading causes of death in people with lupus are health problems that are related to lupus, such as kidney disease, infections, and heart disease.1,2

Work with your doctor to manage lupus. Take your medicine as your doctor tells you to and make healthy choices, such as not smoking, eating healthy foods, getting regular physical activity, and managing your weight. Learn more about managing Lupus.

What research is being done on lupus?

Lupus research focuses on:

  • The genes that play a role in lupus and in the immune system
  • Ways to change the immune system in people with lupus
  • Different symptoms and effects of lupus in different racial and ethnic groups
  • Things in the environment that may cause lupus
  • The role of hormones in lupus
  • Birth control pills and hormone therapy use in women with lupus
  • Heart disease in people with lupus
  • The causes of nervous system damage in people with lupus
  • Treatments for lupus
  • Treatments for organ damage caused by lupus, including stem cell transplantation
  • Getting a better idea of how many people have lupus in the United States

Learn more about current research studies on lupus.

Did we answer your question about lupus diagnosis and treatment?

For more information about lupus diagnosis or treatment, check out the following resources:

*Content on this page is provided by the Office on Women’s Health

Diagnosing and Treating Lupus (2024)

FAQs

What do doctors look for when diagnosing lupus? ›

Your doctor will look for rashes and other signs that something is wrong. Blood and urine tests. The antinuclear antibody (ANA) test can show if your immune system is more likely to make the autoantibodies of lupus. Most people with lupus test positive for ANA.

Why don t doctors like to diagnose lupus? ›

Lupus is a complex disease that is often difficult to diagnose. Risks of diagnostic delays include non-specific signs and symptoms that mimic other diseases and a lack of diagnostic criteria and referral pathways for non-specialists.

How accurate is a lupus diagnosis? ›

Approximately 95% of people with lupus test positive for ANA, but a number of other, non-lupus causes can trigger a positive ANA, including infections and other autoimmune diseases. The ANA test simply provides another clue for making an accurate diagnosis.

What is the most conclusive test for lupus? ›

An antinuclear antibody (ANA) blood test measures the presence of antibodies that are directed against the body's cells, a sign of systemic lupus erythematosus. ANA is present in nearly everyone with active lupus.

What are the 11 markers for lupus? ›

11 criteria for lupus
  • Malar rash: Malar rash also known as butterfly rash is commonly presented on the face. ...
  • Discoid rash: Discoid rash develops in 20 percent of people with SLE and can leave disfiguring scars. ...
  • Photosensitivity: ...
  • Oral ulcers: ...
  • Nonerosive arthritis: ...
  • Serositis: ...
  • Renal disorder: ...
  • Neurologic disorder:

What is the biggest indicator of lupus? ›

Antinuclear antibody (ANA) autoantibodies, or antibodies produced by the immune system that attack the body's own cells, are a hallmark of lupus. ANA is usually measured as 0 to 4+ or as a titer (the number of times a blood sample can be diluted and still be positive).

What is the sister disease to lupus? ›

Overview. Sjogren's (SHOW-grins) syndrome is a disorder of your immune system identified by its two most common symptoms — dry eyes and a dry mouth. The condition often accompanies other immune system disorders, such as rheumatoid arthritis and lupus.

What is a common misdiagnosis of lupus? ›

Sjögren's Syndrome

Sjogren's syndrome, another autoimmune disease, can often be mistaken for lupus. It primarily causes dry eyes and dry mouth but can also cause fatigue and joint pain similar to lupus.

How often do doctors misdiagnose lupus? ›

Lupus is an autoimmune disease that targets your immune system and affects many parts of your body. Its symptoms can vary from person to person and can mimic those of other conditions, leading to a high rate of misdiagnosis. A staggering 46.5% of people with lupus report getting the wrong diagnosis.

What are the 4 criteria for lupus? ›

The ACR criteria include malar rash; discoid rash; photosensitivity (development of a rash after sun exposure); oral or nasal ulcers; arthritis of multiple joints; serositis: (inflammation of the lining around the lungs or heart); kidney disease indicated by protein or casts in the urine; neurological disorders such as ...

What labs are abnormal in lupus? ›

A low white blood cell or platelet count may occur in lupus as well. Erythrocyte sedimentation rate. This blood test determines the rate at which red blood cells settle to the bottom of a tube in an hour. A faster than normal rate may indicate a systemic disease, such as lupus.

Would it be obvious if I had lupus? ›

Lupus can be difficult to diagnose because its signs and symptoms often mimic those of other ailments. The most distinctive sign of lupus — a facial rash that resembles the wings of a butterfly unfolding across both cheeks — occurs in many but not all cases of lupus.

What test is positive in 90% of patients diagnosed with SLE? ›

Why the test is used: Between 75% and 90% of people with lupus have a positive anti-dsDNA test. Also, the test is very specific for lupus. Therefore, a positive test can be useful in confirming a diagnosis. For many people, the titer, or level, of the antibodies rises as the disease becomes more active.

What is the average time to diagnosis lupus? ›

On average, it takes nearly six years for people with lupus to be diagnosed, from the time they first notice their lupus symptoms. A majority (63%) of people with lupus surveyed report being incorrectly diagnosed.

What level of ANA indicates lupus? ›

The ANA test is used specifically for the diagnosis of systemic lupus erythematosis (SLE). A positive ANA titer (> 1:80) with the associated clinical signs (e.g. skin disease, polyarthritis) and laboratory findings (e.g. proteinuria, thrombocytopenia) is diagnostic for SLE.

What does your CBC look like with lupus? ›

There are several results from a CBC that potentially indicate lupus: Low hemoglobin: This sometimes indicates anemia, a common condition for people with lupus. Results less than 13.5 grams per deciliter (g/dL) in males or less than 12 g/dL in females can indicate anemia.

What is included in a lupus panel? ›

A LUPUS blood test includes: Antinuclear Antibodies (ANA) Direct, Complete Blood Count with Differential and Platelets (CBC), Urinalysis Complete, Rheumatoid Arthritis (RA) Factor, Sedimentation Rate (ESR), C-Reactive Protein (CRP) High Sensitivity Cardiac Risk, Comprehensive Metabolic Panel - 14 tests, Prothrombin ...

Top Articles
Latest Posts
Article information

Author: Rueben Jacobs

Last Updated:

Views: 5583

Rating: 4.7 / 5 (57 voted)

Reviews: 88% of readers found this page helpful

Author information

Name: Rueben Jacobs

Birthday: 1999-03-14

Address: 951 Caterina Walk, Schambergerside, CA 67667-0896

Phone: +6881806848632

Job: Internal Education Planner

Hobby: Candle making, Cabaret, Poi, Gambling, Rock climbing, Wood carving, Computer programming

Introduction: My name is Rueben Jacobs, I am a cooperative, beautiful, kind, comfortable, glamorous, open, magnificent person who loves writing and wants to share my knowledge and understanding with you.