Symbicort (budesonide / formoterol): Uses, Side Effects, Alternatives & More - GoodRx (2024)

Symbicort (budesonide / formoterol): Uses, Side Effects, Alternatives & More - GoodRx (1)

What is Symbicort (budesonide / formoterol)?

02:49

Featuring Nabila Ismail, PharmD | Reviewed by Daisy Chau, PharmD, Mera Goodman, MD, FAAP

What is Symbicort (budesonide / formoterol) used for?

  • Asthma

  • Chronic obstructive pulmonary disease (COPD)

How Symbicort (budesonide / formoterol) works

Symbicort (budesonide / formoterol) is a combination of two medications.

  • Budesonide is a corticosteroid that works in your lungs to lower swelling and inflammation, making it easier for you to breathe.

  • Formoterol is a long-acting beta-agonist (LABA) that relaxes the muscles around the airways to the lungs. This opens up the lungs and makes breathing easier.

info

Are you looking for information on budesonide (Pulmicort Respules) or Breztri Aerosphere (budesonide / glycopyrrolate / formoterol) instead?

Drug Facts

Common BrandsSymbicort

Drug ClassIC / LABA

Controlled Substance ClassificationNot a controlled medication

Generic StatusLower-cost generic available

AvailabilityPrescription only

More on Symbicort (budesonide / formoterol) essentials

Albuterol vs. Symbicort: Uses, Side Effects, and MoreWritten by John Maneno, PharmD
Advair vs. Symbicort: A Comprehensive Comparison of Two Popular Asthma and COPD InhalersWritten by Daphne Berryhill, RPh

Symbicort (budesonide / formoterol): Uses, Side Effects, Alternatives & More - GoodRx (4)

Pros and cons of Symbicort (budesonide / formoterol)

Symbicort (budesonide / formoterol): Uses, Side Effects, Alternatives & More - GoodRx (5)

Pros

Long-term treatment for both COPD and asthma

Might feel relief in as soon as 15 minutes for asthma

Safe for children 6 years and older for asthma

Combines two medications into one inhaler for convenience

Symbicort (budesonide / formoterol): Uses, Side Effects, Alternatives & More - GoodRx (6)

Cons

Won't work well for asthma attacks or COPD flare ups

Can cause thrush in mouth or throat as a side effect

Taken 2 times a day

Possible bone loss if used long term

Symbicort (budesonide / formoterol): Uses, Side Effects, Alternatives & More - GoodRx (7)

Pharmacist tips for Symbicort (budesonide / formoterol)

Symbicort (budesonide / formoterol): Uses, Side Effects, Alternatives & More - GoodRx (8)

  • Before using Symbicort (budesonide / formoterol), write down the expiration date (3 months after you open the canister) on the inhaler. Expired medication might not work well for your symptoms. If your inhaler has expired, discard it and obtain a new one from your provider.

    • Symbicort (budesonide / formoterol) is available in two different strengths. Make sure you're using the correct dose directed by your provider. Don't use Symbicort (budesonide / formoterol) more often or at a higher dose than prescribed since it can cause serious side effects.

      • Try to avoid areas that will make your asthma symptoms worse. Always take your rescue inhaler with you when you go outside.

        • Use Symbicort (budesonide / formoterol) every day to control your asthma and COPD symptoms. This isn't an as-needed medication.

          • Symbicort (budesonide / formoterol) isn't used to treat symptoms of an asthma attack or a COPD flare up. If you've wheezing, cough, shortness of breath, chest pain or tightness, let your provider know right away. Make sure you've a rescue inhaler, such as albuterol (Ventolin) in case of an asthma or COPD flare-up.

            • If you were taking oral steroids on a regular basis in the past, make sure to carry a warning card with if you're switching from oral steroids to Symbicort (budesonide / formoterol). The warning card should state that you might need oral steroids during an asthma attack or a COPD flare up.

              • Make sure you get your routine tests done on time while you're taking Symbicort (budesonide / formoterol). This helps your provider make sure this medication is working for you and not causing side effects. Typically the provider will check your blood works, breathing, and eye exams.

                • Before starting any new medications, speak with your provider first. Some medications, such as beta blockers or diuretics ("water pills"), can interact with Symbicort (budesonide / formoterol) and lead to more side effects.

                  How to use Symbicort (budesonide / formoterol):

                  • Before you use each new Symbicort (budesonide / formoterol), shake the inhaler well, and spray 2 puffs into the air to "prime" the medication. If you haven't used it for more than a week or if you dropped it, repeat these steps again. This is to make sure you get the full dose of medication when you inhale it through your mouth.

                    • Take the mouthpiece cover off of the inhaler, and shake the inhaler well. When you're ready, exhale fully. Then, put the mouthpiece into your mouth. Next, inhale deeply as you spray 1 puff into your mouth. Then, move the inhaler away from your mouth, and hold your breath for as long as you can, up to 10 seconds. Repeat the steps for the second puff.

                      • Wipe the mouthpiece with a dry cloth once a week so the medication doesn't build up and block the spray through the mouthpiece.

                        • Clean the mouthpiece with a dry cloth every 7 days. Don't rinse the inhaler with water.

                          • After using Symbicort (budesonide / formoterol), rinse your mouth with water and spit it out right away. This can help lower the chances of developing a fungal infection in your mouth and throat (thrush). If you develop white patches or a cotton-like feeling in the mouth, let your provider know. You might need to take antifungal medication(s) for this side effect.

                            Symbicort (budesonide / formoterol): Uses, Side Effects, Alternatives & More - GoodRx (9)

                            Frequently asked questions about Symbicort (budesonide / formoterol)

                            Is Symbicort (budesonide / formoterol) a steroid?

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                            Symbicort (budesonide / formoterol) is a combination inhaler. One of the medications in Symbicort is budesonide, an inhaled steroid. It helps you breath better by lowering swelling and inflammation in your lungs. Symbicort also contains formoterol, which is a long-acting beta-agonist (LABA) that relaxes your airway muscles and opens up your lungs. Both of these medications work together to control symptoms of asthma or COPD.

                            Is Symbicort (budesonide / formoterol) a rescue inhaler?

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                            Symbicort (budesonide / formoterol) isn't a rescue inhaler; it's a long-term maintenance medication for asthma and COPD. You should only use a rescue inhaler, such as albuterol (Ventolin), to treat sudden shortness of breath, wheezing, and cough. Symbicort (budesonide / formoterol) won't work quickly enough to treat asthma or COPD flare-ups. But if you use it regularly, it'll help control your symptoms enough so that you don't need to reach for your rescue inhaler as often. If you've been taking Symbicort (budesonide / formoterol) for a while and still experiencing breathing problems regularly, let your provider know. They can see if you're using the inhaler correctly and let you know whether you need additional medications.

                            How long does it take for Symbicort (budesonide / formoterol) to work?

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                            In a clinical study, few people experienced relief from asthma symptoms within 15 minutes of taking Symbicort (budesonide / formoterol). But you'll need to take it regularly for 2 weeks or longer to experience the maximum benefit of this medication. Because of this, it's important for you to have a rescue inhaler on hand in case of sudden shortness of breath, wheezing, or cough.

                            How long can you be on Symbicort (budesonide / formoterol)?

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                            You should use Symbicort (budesonide / formoterol) as long as your provider directs you to. Typically, Symbicort (budesonide / formoterol) is inhaled twice daily, even if you aren't experiencing breathing problems. Using this medication regularly can help you prevent flare ups and control symptoms of asthma and COPD over time.

                            Does Symbicort (budesonide / formoterol) cause weight gain?

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                            People didn't report weight gain as a side effect of Symbicort (budesonide / formoterol) in clinical trials. While oral steroids, such as prednisone are known to cause weight gain, it's unlikely that inhaled steroids will have the same risk for side effects if you're taking them as directed. If you're concerned about weight gain with Symbicort (budesonide / formoterol), talk with your provider.

                            Symbicort (budesonide / formoterol): Uses, Side Effects, Alternatives & More - GoodRx (10)

                            What are the risks and warnings for Symbicort (budesonide / formoterol)?

                            Symbicort (budesonide / formoterol) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

                            Symbicort (budesonide / formoterol): Uses, Side Effects, Alternatives & More - GoodRx (11)

                            Risk of worsening of asthma or COPD

                            • Risk factors: Using Symbicort (budesonide / formoterol) during asthma attacks or severe episodes of asthma | Using more doses of Symbicort (budesonide / formoterol) than prescribed

                              Although rare, Symbicort (budesonide / formoterol) can worsen symptoms of asthma or COPD by tightening the airways. This medical condition is called paradoxical bronchospasm and can be life-threatening if not treated quickly. If you feel more wheezing, shortness of breath, or coughing after using Symbicort (budesonide / formoterol), stop this medication right away and speak to your provider.

                              In addition, Symbicort (budesonide / formoterol) shouldn't be used to treat asthma attacks or any severe episodes of asthma or COPD. You should only use a rescue inhaler, such as albuterol (ProAir), to treat asthma attacks or COPD flare ups. If your rescue inhaler isn't working well to control your symptoms, let your provider know because you might need additional medications, such as steroid pills.

                              Symbicort (budesonide / formoterol): Uses, Side Effects, Alternatives & More - GoodRx (12)

                              Overdose

                              • Risk factors: Using too much Symbicort (budesonide / formoterol) | Using together with other LABAs

                                Using Symbicort (budesonide / formoterol) more often, at a higher dose than prescribed, or together with another LABA (e.g., Striverdi Respimat (olodaterol)) can raise the risk of overdose. Get medical attention right away if you think you've taken too much of this medication or have symptoms of overdose, including chest pain, fast heartbeat, dizziness, headache, dry mouth, muscle cramps, nausea, or trouble sleeping.

                                Symbicort (budesonide / formoterol): Uses, Side Effects, Alternatives & More - GoodRx (13)

                                Fungal infection in the mouth (oral thrush)

                                • Risk factor: Not rinsing mouth after using Symbicort (budesonide / formoterol)

                                  There's a chance of fungal infections, such as thrush in the mouth and throat, while using Symbicort (budesonide / formoterol). The risk is higher if you don't rinse your mouth right after using this medication. Symptoms of oral thrush include white patches on the inside of the mouth, mouth redness or soreness, and pain while eating or swallowing. If you develop thrush in your mouth, let your provider know right away. You will need to take an antifungal medication to treat the infection.

                                  Symbicort (budesonide / formoterol): Uses, Side Effects, Alternatives & More - GoodRx (14)

                                  Higher risk of infection

                                  • Risk factors: Active, chronic (long-term), or recurrent infection | Medical conditions that weaken the immune system | Taking other medications that can weaken the immune system

                                    Symbicort (budesonide / formoterol) can lower your ability to fight infections. Infections, such as tuberculosis (TB), chickenpox, and measles, can be more serious in people who use Symbicort (budesonide / formoterol). If you have any of the risk factors listed above, discuss with your provider about how you can safely use this medication. Don't use Symbicort (budesonide / formoterol) if you have an active infection or an infection that keeps coming back without speaking with your provider first. Symbicort (budesonide / formoterol) can make these infections worse. Let your provider know right away if you have signs or symptoms of an infection, such as fever, cough, white patches in your mouth, or sore throat.

                                    Additionally, Symbicort (budesonide / formoterol) can also raise the risk of certain lung infections, including pneumonia. Keep in mind that symptoms of pneumonia are similar to COPD flare ups, so let your provider know if you experience cough, chest pain, shortness of breath. Your provider can help decide what is the right treatment for you.

                                    Symbicort (budesonide / formoterol): Uses, Side Effects, Alternatives & More - GoodRx (15)

                                    Switching from oral to inhaled steroids

                                    • Risk factors: Long-term use of oral steroids | Suddenly stopping prednisone 20 mg or equivalent dose of steroid | History of asthma or COPD

                                      When switching from an oral to an inhaled steroid, your provider might closely observe you for withdrawal symptoms, such as nausea, tiredness, weakness, or muscle and joint pain. This is because switching between different forms of steroids can affect the cortisol levels in your body. Cortisol is a steroid hormone that controls blood sugar, blood pressure, and other important functions in your body. It also helps the body respond to stressful situations, such as trauma, surgery, and infection. Don't switch between steroids without proper guidance from your provider. Let your provider know if you develop any symptoms, such as tiredness, weakness, loss of energy, nausea, vomiting, or low blood pressure.

                                      If you have used oral steroids for long periods of time and have asthma or COPD, it's important to carry a warning card with you that states that you might need steroid pills during an asthma attack or a COPD flare up. In these cases, a rescue inhaler alone might not be enough to treat your emergency. Your provider might also perform tests to monitor your lung function and breathing more closely.

                                      Symbicort (budesonide / formoterol): Uses, Side Effects, Alternatives & More - GoodRx (16)

                                      Reduced adrenal gland function

                                      • Risk factors: Using high potency steroids | Using steroids for a long period of time | Using oral steroids | Stressful events (e.g., surgery)

                                        Rarely, using inhaled steroids, such as Symbicort (budesonide / formoterol), for a long time can cause a medical condition called adrenal suppression. This happens when your adrenal gland doesn't make enough of steroid hormones for your body, which creates a dependence on steroid medication. If you suddenly stop the medication, it can be dangerous to your body. In adults, symptoms of withdrawal include fever, joint or muscle pain, and low energy. In children, symptoms often include stunted growth, weight gain, and headaches. To prevent adrenal suppression from happening, your provider will prescribe the lowest possible dose of Symbicort (budesonide / formoterol) that works well for you for the shortest amount of time. If you need to use Symbicort (budesonide / formoterol) for a long period of time, their provider might ask you to do some lab work to test how well your adrenal gland works. Let your provider know if you have symptoms of withdrawal. Don't suddenly stop using Symbicort (budesonide / formoterol) without talking to your provider first.

                                        Symbicort (budesonide / formoterol): Uses, Side Effects, Alternatives & More - GoodRx (17)

                                        Heart problems

                                        • Risk factors: History of heart problems or nerve problems | Using too much Symbicort (budesonide / formoterol) | Using together with other LABAs

                                          Rarely, using too much Symbicort (budesonide / formoterol) can cause serious problems, including seizures, heart problems, and changes in blood pressure. To lower your risk, don't use Symbicort (budesonide / formoterol) with other inhalers that have LABA (e.g., Formoterol (Perforomist)) and don't use this medication more than directed. Talk to your provider right away if you experience chest pain, fast heart rate, headache, tremor, nausea, dizziness, and trouble sleeping.

                                          Symbicort (budesonide / formoterol): Uses, Side Effects, Alternatives & More - GoodRx (18)

                                          Risk of bone loss and poor growth

                                          • Risk factors: Using Symbicort (budesonide / formoterol) long term | Unable to move for a long period of time | Family history of osteoporosis | Poor diet | Using medications that can cause bone loss

                                            People taking Symbicort (budesonide / formoterol) for a long time might be at risk of bone loss or poor growth. If you've any of the risk factors listed above, you might be more likely to experience weaken bones or slowed growth after using Symbicort (budesonide / formoterol) long-term. Your provider might measure your bone density regularly to make sure your bones are healthy. If you've had bone fractures before or history of osteoporosis, talk to your provider about their risk before using this medication.

                                            Symbicort (budesonide / formoterol): Uses, Side Effects, Alternatives & More - GoodRx (19)

                                            Eye problems

                                            • Risk factors: Long-term use of Symbicort (budesonide / formoterol) | History of eye problems like glaucoma or cataracts

                                              Using Symbicort (budesonide / formoterol) for a long time can raise eye pressure, worsen glaucoma, and cause cataracts (cloudiness in the eyes). Talk to your provider right away if you experience blurry vision, eye discomfort, or other changes in your vision after using Symbicort (budesonide / formoterol). You might need an eye exam.

                                              Symbicort (budesonide / formoterol): Uses, Side Effects, Alternatives & More - GoodRx (20)

                                              Serious allergic reaction

                                              • Risk factor: History of allergy to medications containing budesonide

                                                In some rare cases, Symbicort (budesonide / formoterol) can cause allergic reactions, which can be life-threatening. Don't use this medication if you've a history of allergy to medications containing budesonide. Watch out for signs and symptoms of allergic reactions, such as wheezing, dizziness, fainting, rash, itching, trouble breathing, and swelling of the tongue or throat. Get medical attention right away if you've any of these reactions.

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                                                Low potassium and high blood sugar levels

                                                Symbicort (budesonide / formoterol) can cause low potassium levels in some people, which can affect your heart rhythm. The low levels of potassium are typically temporary and usually doesn't require any treatment. Let your provider know if you have muscle pain or weakness, muscle cramps, or abnormal heartbeat as these can be signs of low potassium.

                                                Although rare, Symbicort (budesonide / formoterol) can also raise blood sugar levels in some people. Let your provider know if you're feeling more thirsty or hungry than usual, confused, or urinating more often. These can be signs of high blood sugar.

                                                Symbicort (budesonide / formoterol): Uses, Side Effects, Alternatives & More - GoodRx (22)

                                                Symbicort (budesonide / formoterol) dosage forms

                                                Symbicort (budesonide / formoterol): Uses, Side Effects, Alternatives & More - GoodRx (23)

                                                Inhaler

                                                DosageAs low as
                                                120 doses of 80mcg/4.5mcg$211.62 for 1 inhaler
                                                120 doses of 160mcg/4.5mcg$239.64 for 1 inhaler

                                                Typical dosing for Symbicort (budesonide / formoterol)

                                                Symbicort (budesonide / formoterol) comes in two different strengths:

                                                • Each inhalation of Symbicort 80/4.5 contains 80 mcg of budesonide and 4.5 mcg of formoterol.

                                                • Each inhalation of Symbicort 160/4.5 contains 160 mcg of budesonide and 4.5 mcg of formoterol.

                                                Asthma

                                                • Adults and children age 12 years and older: The typical dose is 2 inhalations of Symbicort 80/4.5 or Symbicort 160/4.5 twice daily.

                                                • Children ages 6-11 years old: The typical dose is 2 inhalations of Symbicort 80/4.5 by mouth twice a day.

                                                COPD

                                                • Adults: The typical dose is 2 inhalations of Symbicort 160/4.5 by mouth twice a day.

                                                Symbicort (budesonide / formoterol): Uses, Side Effects, Alternatives & More - GoodRx (24)

                                                How much does Symbicort (budesonide / formoterol) cost?

                                                To access savings, use a GoodRx coupon and pay just a fraction of the retail price.

                                                Symbicort (brand)

                                                savings_outlinedGoodRx lowest price$239.64(save 46.28%)

                                                Symbicort (budesonide / formoterol) (generic)

                                                savings_outlinedGoodRx lowest price$109.29(save 58.08%)

                                                Symbicort (budesonide / formoterol): Uses, Side Effects, Alternatives & More - GoodRx (25)

                                                Symbicort (budesonide / formoterol) contraindications

                                                Contraindications are specific health conditions or situations in which a person shouldnot take a medication due to safety concerns. If you have any of the following conditionsor if any of the following apply to you, let your healthcare provider know because Symbicort (budesonide / formoterol) will not be safe for you to take.

                                                • Asthma attacks

                                                • Severe episodes of asthma or COPD

                                                Symbicort (budesonide / formoterol): Uses, Side Effects, Alternatives & More - GoodRx (26)

                                                What are alternatives to Symbicort (budesonide / formoterol)?

                                                There are a number of medications that your doctor can prescribe in place of Symbicort (budesonide / formoterol). Compare a few possible alternatives below.

                                                Symbicort (budesonide / formoterol)

                                                Used for:

                                                • Asthma

                                                • Chronic obstructive pulmonary disease (COPD)

                                                $109.29 Lowest GoodRx priceView Prices

                                                Dulera (mometasone / formoterol)

                                                Used for:

                                                • Maintenance treatment of asthma in adults and children age 5 years and older

                                                $343.20 Lowest GoodRx priceView Prices

                                                Advair (fluticasone / salmeterol)

                                                Used for:

                                                • Maintenance treatment of asthma

                                                • Maintenance treatment of COPD - Advair Diskus 250/50 only

                                                $87.99 Lowest GoodRx priceView Prices

                                                Symbicort (budesonide / formoterol): Uses, Side Effects, Alternatives & More - GoodRx (2024)
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